Dr. Biesman has been performing clinical research for nearly 30 years. Over this period of time he has played an active role in the development and testing of many drugs, lasers and other energy-based devices (e.g. Thermage®, CoolSculpting®, Ultherapy®, Sofwave®, and Fraxel® to name a few), topical products and injectables (Botox®, Juvederm®, Restylane®, Daxxify® and many others). Clinical research remains an extremely important part of his practice today. Dr. Biesman helps design and execute trials that evaluate new developments in health care in a scientific and controlled way. This not only helps drive advances in patient care and early access to the newest products but ensures that the highest standards are observed during the evaluation process.

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Dr. Biesman has a professional, experienced, and dedicated research team. We take great pride in providing quality care for our patients and providing quality data for our sponsors.

Our research team is highly trained and qualified.

Qualifications & Certifications:

  • American Board of Ophthalmology Certified Physician
  • All research staff are GCP certified (Good Clinical Practice)
  • All research staff are NIH certified (National Institute of Health of Human Subjects)
  • Clinical Laboratory Improvement Amendments (CLIA) Waiver
  • All research staff are HIPAA/OSHA trained
  • All research staff are CPR certified
  • IATA Dangerous Goods Certificate
  • Broad Range of eCRF experience


Dr. Biesman Staff

Dr. Brian Biesman

Dr. Brian Biesman has nearly 30 years of experience as a Principal Investigator for clinical trials. He has completed well over 100 trials evaluating pharmaceuticals, energy-based devices and topically applied medications and products. He conducts both sponsored trials and Investigator Initiated Trials. Dr. Biesman has extensive experience designing and reviewing clinical trial protocols. He also has a great deal of regulatory expertise, having collaborated and communicated with the Food and Drug Administration (FDA) as a subject expert on various treatments. Dr. Biesman maintains a reputation for being a PI who is extremely involved in all aspects of the trials he oversees. Research is a passion of his and is a very important part of his practice.

Molly Katz, RN

Molly Katz, RN has extensive clinical trial experience, routinely functioning as an Evaluating Investigator for registration trials, an evaluator in scale development and as a sub-investigator. Molly is extremely accomplished as a facial aesthetics expert having worked alongside Dr. Biesman for more than 12 years as an aesthetic nurse and surgical first assistant. Molly is also a preceptor in the Vanderbilt University Oculofacial Plastic Surgery Fellowship. Prior to working with Dr. Biesman Molly had many years of experience as a cardiac and critical care nurse.

Amanda Smith, CCRC

Amanda Smith, our Lead Clinical Research Coordinator, has 10 years of clinical research experience. Amanda maintains a CCRC certification and has been the Lead Coordinator for our site for over 5 years. Amanda specializes in recruitment, subject retention, quality control and study start up. Amanda also acts as an independent consultant to assist sponsors optimize protocols, create source documents, advise on recruitment and retention, etc.

Dr. Yash Vaishnav

Dr. Yash Vaishnav serves as a Sub-Investigator on some of our projects. Dr. Yash is completing his fellowship in Oculofacial Plastic Surgery at the prestigious Vanderbilt University ASOPRS Fellowship program.

Cara Costner, RN FNP

Cara Costner RN, FNP has been participating in clinical research for many years. She regularly serves as an Evaluating Investigator on clinical trials and was a co-investigator on several trials that led to the development of the DESCRIBE patch. Cara has been a clinical aesthetic nurse with Dr. Biesman for over 10 years. Prior to joining Dr. Biesman’s team Cara worked as a neonatal intensive care nurse.

Tammy Holton, RN BSN

Tammy Holton, RN is a laser and skin care specialist at our site. She has worked on clinical trials using energy-based devices, topical skincare products, and chemical peels. Tammy has worked with Dr. Biesman for more than 14 years. Before entering the realm of aesthetics Tammy worked in critical care and cardiac nursing.


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